According to findings published in the Journal of Clinical Lipidology, the lowest levels of the sunshine vitamin were associated with a 31 per cent prevalence of metabolic syndrome, compared to only 10 per cent for people wit the highest average levels.
“Although previous surveys have also reported associations between low 25(OH)D concentration and metabolic syndrome components, to our knowledge, the present investigation is the first to report this finding in a sample with a high prevalence of vitamin D dietary supplement users in which frequencies of vitamin D insufficiency and deficiency were low,” wrote the researchers, led by Kevin Maki from Illinois-based Provident Clinical Research
Metabolic syndrome (MetS) is a condition characterised by central obesity, hypertension, and disturbed glucose and insulin metabolism. The syndrome has been linked to increased risks of both type-2 diabetes and cardiovascular disease (CVD).
“The most notable finding from the present study was the strong relationship between serum concentrations of 25(OH)D and HDL-C concentrations,” wrote the researchers.
They also observed inverse associations between vitamin D levels and triglyceride levels, body mass index, and waist circumference, meaning that higher vitamin D levels were associated with lower values for these measurables.
Source: Journal of Clinical Lipidology
Published online ahead of print, doi: 10.1016/j.jacl.2009.07.003
“Serum 25-Hydroxyvitamin D is Independently Associated with High Density Lipoprotein Cholesterol and the Metabolic Syndrome in Men and Women”
Authors: K.C. Maki, M.R. Rubin, L.G. Wong, J.F. McManus, C.D. Jensen, J.W. Marshall, A. Lawless